Webinar: Beyond Epitope Mapping - POCTRN
Center news
Webinar: Beyond Epitope Mapping
To evaluate the impact of variant mutations on rapid antigen tests our speakers developed a mammalian surface-display platform for SARS-CoV-2 Nucleocapsid protein, the target of the majority of antigen tests. They employed deep mutational scanning to evaluate binding of all possible Nucleocapsid point mutations to diagnostic antibodies. This approach generates unique escape mutation profiles for each antibody which serve as a valuable resource for predicting performance of antigen tests against past, current, as well as future variants of SARS-CoV-2.
Speakers
Filipp Frank, PhD, Department of Biochemistry, Emory University
Eric Ortlund, PhD, Professor, Department of Biochemistry, Emory University
When
April 19, 2022
2PM ET
RADx: Rapid Acceleration of Diagnostics
In response to the COVID-19 pandemic, the Rapid Acceleration of Diagnostics (RADxsm) initiative was formed to accelerate the development, validation, and commercialization of innovative point-of-care and home-based tests, as well as improvements to clinical laboratory tests, that can directly detect SARS-CoV-2, the virus that causes COVID-19.
In the News
NIH RADx initiative expands COVID-19 testing innovation for additional types of rapid tests
The need for new test verification and regulatory support for innovative diagnostics
NIH-funded screening study builds case for frequent COVID-19 antigen testing
RADx partnerships speed new COVID testing
Publication reveals essential ingredients of the groundbreaking NIH RADx national diagnostics effort
RADx Expects COVID-19 Portfolio to Accelerate an Era of At-Home Infectious Disease Testing (Login Required)
COVID-19 Testing: Three Breakthrough Solutions in the RADx Initiative
The National Strategy From the COVID-19 Response and Pandemic Preparedness